From Chapter 4:
Among the documents in the possession of the Society of Antiquaries of Scotland there is a letter patent under the great seal of Charles I, in 1634, granted for the purpose of correcting the irregular sales and restraining the immoderate use of tobacco in Scotland. The letter states that tobacco was used on its first introduction as a medicine, but had since been so largely indulged in and was frequently of such bad quality, as not only to injure the health, but deprave the morals of the King's subjects. These were sentiments worthy of King James. Mr. Matthew Livingstone, who has calendared this document, says that the King therein proceeds, in order to prevent such injurious results of the use of tobacco, to appoint Sir James Leslie and Thomas Dalmahoy to enjoy for seven years the sole power of appointing licensed vendors of the commodity. These vendors, after due examination as to their fitness, were to be permitted, on payment of certain compositions and an annual rent in augmentation of the King's revenue, to sell tobacco in small quantities. The letter further directs that the licensees so appointed shall become bound to sell only sound tobacco—an admirable provision, if a trifle difficult to enforce—and to keep good order in their houses and shops. "The latter clause," adds Mr. Livingstone, "would almost suggest that the tobacco was to be sold for consumption on the premises,"—as I have no doubt it was—"and that the smokers were probably in the habit at their symposiums of using, even as they may still, I dare say, other indulgences not so soothing in their effects as the coveted weed"—a suggestion for which there seems little foundation in the clause to which Mr. Livingstone refers.

From Chapter 5:
Among the many medicinal virtues attributed to tobacco was its supposed value as a preservative from contagion at times of plague. Hearne, the antiquary, writing early in 1721, said that he had been told that in the Great Plague of London of 1665 none of those who kept tobacconists' shops suffered from it, and this belief no doubt enhanced the medical reputation of the weed. I have also seen it stated that during the cholera epidemics of 1831, 1849, and 1866 not one London tobacconist died from that disease; but good authority for the statement seems to be lacking. Hutton, in his "History of Derby," says that when that town was visited by the plague in 1665, that at the "Headless-cross ... the market-people, having their mouths primed with tobacco as a preservative, brought their provisions.... It was observed, that this cruel affliction never attempted the premises of a tobacconist, a tanner or a shoemaker." Whatever ground there may have been for the belief in the prophylactic effect of smoking, there can be no doubt that in the seventeenth century it was firmly held. Howell in one of his "Familiar Letters" dated January 1, 1646, says that the smoke of tobacco is "one of the wholesomest sents that is against all contagious airs, for it overmasters all other smells, as King James they say found true, when being once a hunting, a showr of rain drave him into a Pigsty for shelter, wher he caus'd a pipe full to Be taken of purpose." But here Mr. Howell is certainly drawing the long-bow. One cannot imagine the author of the "Counterblaste" countenancing the use of tobacco under any circumstances.